Davide Seruggia earns FWF Stand-Alone funding
To find vulnerabilities of cancers that are driven by MYC, a protein known for its potential to induce tumor growth, is the goal of a new project funded by the Austrian Science Fund FWF. Davide Seruggia from St. Anna Children’s Cancer Research Institute (St. Anna CCRI) and colleagues aim to deactivate this key cancer regulator by targeting components of SAGA, a protein complex tightly linked to MYC. Since pediatric leukemia and neuroblastoma, two of the most common childhood cancers are known to be driven by MYC, establishing new strategies to interrupt its activity in cancer cells is of utmost importance.